Time variation in the inflation passthrough of energy prices

From Bayesian estimates of a vector autoregression (VAR) which allows for both coefficient drift and stochastic volatility, we obtain the following three results. First, beginning in approximately 1975, the responsiveness of core inflation to changes in energy prices in the United States fell rapidly and remains muted. Second, this decline in the passthrough of energy inflation to core prices has been sustained through a recent period of markedly higher volatility of shocks to energy inflation. Finally, reduced energy inflation passthrough has persisted in the face of monetary policy which quickly became less responsive to energy inflation starting around 1985.

The Transmission of Price Trends from Consumers to Producers and Tests of Market Power

This study examines the competitiveness of four Canadian agricultural industries (eggs, milk, chicken and turkey) using a general equilibrium farm to retail pricing model developed by Wohlgenant (1989). The model generates retail and farm pricing equations that are estimated using maximum likelihood developed by Johansen (1992). The results indicate that in all cases, long-run constant returns is rejected, indicating market power within the Canadian retail to farm marketing sector. The model also finds more cointegrating vectors than predicted by theory, also inconsistent with competitive markets. Results are based on commercial disappearance as a proxy for consumer demand and therefore confounding between uncompetitive markets and quality differences may be indicated. Less ambiguous results would be obtained if consumer expenditures rather than commercial disappearance data were available. Still, results are rather emphatic in rejection of competitive markets in food markets in Canada. More competitive markets are indicated in the United States using similar methods.Market power, food processing, cointegration, Agribusiness, Agricultural and Food Policy, Consumer/Household Economics, Demand and Price Analysis, Food Consumption/Nutrition/Food Safety, D41, L66, Q13,

Don’t Leave the Faculty at the Station: Introducing Faculty to Collection Development Grants

In 2012, a collection analysis report was published outlining the results of a year‐long study of the College of William and Mary Library collections comparing it to those of other peer institutions using OCLC’s collection analysis software. As a means to address some of the deficiencies brought out in the report as well as provide outreach and curricular support, the library began to offer collection development grants to college faculty. This has been a fruitful experience to build collaborative efforts with faculty; to fill gaps in the library collections; enhance curricular and faculty research support; and to provide outreach to the faculty community through library liaisons

Direct Detection and Sequencing of Damaged DNA Bases

Products of various forms of DNA damage have been implicated in a variety of important biological processes, such as aging, neurodegenerative diseases, and cancer. Therefore, there exists great interest to develop methods for interrogating damaged DNA in the context of sequencing. Here, we demonstrate that single-molecule, real-time (SMRT®) DNA sequencing can directly detect damaged DNA bases in the DNA template - as a by-product of the sequencing method - through an analysis of the DNA polymerase kinetics that are altered by the presence of a modified base. We demonstrate the sequencing of several DNA templates containing products of DNA damage, including 8-oxoguanine, 8-oxoadenine, O6-methylguanine, 1-methyladenine, O4-methylthymine, 5-hydroxycytosine, 5-hydroxyuracil, 5-hydroxymethyluracil, or thymine dimers, and show that these base modifications can be readily detected with single-modification resolution and DNA strand specificity. We characterize the distinct kinetic signatures generated by these DNA base modifications

Physical testing and strength and conditioning practices differ between coaches working in academy and first team soccer

Scientific guidelines exist regarding strength and conditioning (S&C) best practice, for both first team and academy level soccer. However, it is not known if these research-informed guidelines are followed in such applied settings. The aim of this study was to investigate current S&C practice in first team and academy level (men's and women's) soccer, in multiple countries/continents. A total of 170 participants, who were involved with the delivery of S&C support at their soccer club, completed a comprehensive survey, describing their training methods. Data were analysed using Pearson's chi-square test of independence and independent t-tests. Statistical significance was set to p < 0.05. A greater proportion of academy compared to first team coaches assessed acceleration/sprint (92% vs. 83%, p=0.026), jump (95% vs. 83%, p=0.023) and change of direction performance (77% vs. 61%, p=0.031). The weekly training structure differed between groups, particularly within women's squads, with women's academy coaches reporting the lowest session frequency of all groups (1.59 ± 0.62 session per week, 44 ± 17 min duration). A greater proportion of academy (54%) versus first team (35%) coaches prioritised bodyweight training (p=0.031), despite a similar distribution of movement patterns trained. Overall, 44% S&C coaches reported using training intensities below strength training guidelines (≥80% 1RM). To conclude, there were many differences in S&C practice between S&C coaches working with first team and academy squads but particularly noteworthy was the greater proportion of academy coaches prioritising bodyweight training compared to first team coaches, which may limit physical development in academy players

Fullerene van der waals Oligomers as electron traps

Density functional theory calculations indicate that van der Waals fullerene dimers and larger oligomers can form interstitial electron traps in which the electrons are even more strongly bound than in isolated fullerene radical anions. The fullerenes behave like super atoms , and the interstitial electron traps represent one-electron intermolecular σ-bonds. Spectroelectrochemical measurements on a bis-fullerene-substituted peptide provide experimental support. The proposed deep electron traps are relevant for all organic electronics applications in which non-covalently linked fullerenes in van der Waals contact with one another serve as n-type semiconductors

Global differences in current strength and conditioning practice within soccer

Differences exist between top-tier soccer leagues (e.g. anthropometry and match demands), which may influence strength and conditioning (S&C) practice. Thus, the aim of this study was to investigate whether current S&C practice in men's and women's (first team and academy) squads differed between global regions. A total of 170 participants, involved in the delivery of S&C support at their soccer club (based on South America (SA), the USA, the UK, or other European countries (EUR)), completed a survey examining their S&C methods. The survey comprised six sections: (i) academic qualifications and S&C coaching experience; and their preferred methods for (ii) physical testing; (iii) strength and power development; (iv) plyometric training; (v) speed development; and (vi) periodization. Coaches in EUR conducted fewer formal S&C sessions, placed less importance on free-weight resistance training (RT), and performed less speed and plyometric training compared to coaches in other global regions (all p<0.05). While coaches working with UK squads devoted more time to physical development than those in EUR, they regarded bodyweight training as the most important RT modality in comparison to USA and SA, who prioritized free-weight RT. Finally, SA academy players are introduced to formal S&C later (14 years old) than those in the UK (12 years old, p=0.002). However, it is reasonable to suggest that the S&C practice of coaches in the USA and SA align better with scientific guidelines for strength and power development in soccer, with emphasis on free-weight RT alongside regular sprint and plyometric training, compared to coaches in the UK and EUR

High energy from space

The following subject areas are covered: (1) important scientific problems for high energy astrophysics (stellar activity, the interstellar medium in galaxies, supernovae and endpoints of stellar evolution, nucleosynthesis, relativistic plasmas and matter under extreme conditions, nature of gamma-bursts, identification of black holes, active nuclei, accretion physics, large-scale structures, intracluster medium, nature of dark matter, and the X- and gamma-ray background); (2) the existing experimental programs (Advanced X-Ray Astrophysics Facility (AXAF), Gamma Ray Observatory (GRO), X-Ray Timing Explorer (XTE), High Energy Transient Experiment (HETE), U.S. participation in foreign missions, and attached Shuttle and Space Station Freedom payloads); (3) major missions for the 1990's; (4) a new program of moderate missions; (5) new opportunities for small missions; (6) technology development issues; and (7) policy issues

Conserved and unique transcriptional features of pharyngeal arches in the skate (Leucoraja erinacea) and evolution of the jaw

© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Hirschberger, C., Sleight, V. A., Criswell, K. E., Clark, S. J., & Gillis, J. A. Conserved and unique transcriptional features of pharyngeal arches in the skate (Leucoraja erinacea) and evolution of the jaw. Molecular Biology and Evolution, (2021): msab123, https://doi.org/10.1093/molbev/msab123The origin of the jaw is a long-standing problem in vertebrate evolutionary biology. Classical hypotheses of serial homology propose that the upper and lower jaw evolved through modifications of dorsal and ventral gill arch skeletal elements, respectively. If the jaw and gill arches are derived members of a primitive branchial series, we predict that they would share common developmental patterning mechanisms. Using candidate and RNAseq/differential gene expression analyses, we find broad conservation of dorsoventral patterning mechanisms within the developing mandibular, hyoid and gill arches of a cartilaginous fish, the skate (Leucoraja erinacea). Shared features include expression of genes encoding members of the ventralising BMP and endothelin signalling pathways and their effectors, the joint markers nkx3.2 and gdf5 and pro-chondrogenic transcription factor barx1, and the dorsal territory marker pou3f3. Additionally, we find that mesenchymal expression of eya1/six1 is an ancestral feature of the mandibular arch of jawed vertebrates, while differences in notch signalling distinguish the mandibular and gill arches in skate. Comparative transcriptomic analyses of mandibular and gill arch tissues reveal additional genes differentially expressed along the dorsoventral axis of the pharyngeal arches, including scamp5 as a novel marker of the dorsal mandibular arch, as well as distinct transcriptional features of mandibular and gill arch muscle progenitors and developing gill buds. Taken together, our findings reveal conserved patterning mechanisms in the pharyngeal arches of jawed vertebrates, consistent with serial homology of their skeletal derivatives, as well as unique transcriptional features that may underpin distinct jaw and gill arch morphologies.This work was supported by a Biotechnology and Biological Sciences Research Council Doctoral Training Partnership studentship to CH, by a Wolfson College Junior Research Fellowship and MBL Whitman Early Career Fellowship to VAS, and by a Royal Society University Research Fellowship (UF130182 and URF\R\191007), Royal Society Research Grant (RG140377) and University of Cambridge Sir Isaac Newton Trust Grant (14.23z) to JAG